Nurse Anesthetist Salary in Mount Pleasant, SC: $231,078 (2026)
Quick Answer:A full-time nurse anesthetist in Mount Pleasant, SC earns a median $231,078/year (≈ $111.09/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Mount Pleasant's price level (8% below national, BEA RPP 91.5), that paycheck buys what $252,544 would nationally. Nominal pay sits 1.5% above the South Carolina state average.
Based on BLS state-level estimates · View source

In Mount Pleasant, South Carolina, the compensation landscape for nurse anesthetists in 2026 reflects a substantial median salary of $231,078, making it slightly lower than the national average of $248,893. The salary range spans from $152,210 at the 10th percentile to $325,582 at the 90th percentile, indicating significant variance in earnings based on local employment structure and practice locations. For professionals in this field, choosing between W-2 hospital employment and 1099 arrangements through group practices or locum tenens can significantly affect annual earnings and job satisfaction. Moreover, the estimates are drawn from 2025 BLS state-level data and adjusted for the region's cost of living dynamics, which is somewhat below the national average.
About the Mount Pleasant Market
Salary estimated from South Carolina average ($208,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $152,210 | $73.18 |
| Lower Range (P25) | $195,736 | $94.10 |
| Median (P50)(typical) | $231,078 | $111.09 |
| Upper Range (P75) | $285,440 | $137.23 |
| Top Earners (P90) | $325,582 | $156.53 |
Median Salary Position
7.16% below the national average
2026 Salary Percentile Distribution in Mount Pleasant
In Mount Pleasant, SC, the nurse anesthetist salary spread from the 10th to 90th percentile is $173,372 (2026 est.). At $231,078, the local median is 7.16% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Mount Pleasant: You'd be in the lower-middle range
How Mount Pleasant Nurse Anesthetist Pay Compares
Mount Pleasant median: $231,078/year (2026)
| Compared To | Median Salary | Mount Pleasant Pays |
|---|---|---|
| South Carolina Average | $227,663 | +1.50% more |
| National Average | $248,893 | -7.16% less |
Nurse Anesthetists in Mount Pleasant, SC earn a median of $231,078 per year (2026 est.), which is 7.16% lower than the national median of $248,893 and 1.50% above the South Carolina state average of $227,663.
Cost-of-Living Adjusted Salary
Mount Pleasant has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Mount Pleasant, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse anesthetist earning $231,078 nominally has purchasing power equivalent to $252,544 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$162,279
2025 BLS Actual
$219,656
2026 Current Est.
$231,078
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Mount Pleasant (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $162,279 | Actual |
| 2020 | $170,440 | Actual |
| 2021 | $181,609 | Actual |
| 2022 | $188,554 | Actual |
| 2023 | $197,430 | Actual |
| 2024 | $193,112 | Actual |
| 2025 | $219,656 | Actual |
| 2026(current) | $231,078 | Estimated |
| 2027 | $243,094 | Projected |
Based on 7 years of BLS OEWS data for the Mount Pleasant metropolitan area, the median nurse anesthetist salary grew 35.4% from $162,279 (2019) to $219,656 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $243,094 by 2027 — a total increase of $80,815 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Mount Pleasant metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $152,210 – $195,736 |
| 3-5 years (Mid Career) | $195,736 – $231,078 |
| 5+ years (Experienced) | $231,078 – $285,440 |
| 10+ years (Top Earner) | $285,440 – $325,582 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Mount Pleasant
Within the local job market, Mount Pleasant hosts 19 nurse anesthetists, indicating a moderate level of demand for these specialists. The cost of living index at 91.5 suggests that the purchasing power of salaries here may be more favorable than in higher-cost areas, making the effective compensation more appealing. Compensation tends to be higher at local hospital systems that employ nurse anesthetists on a W-2 basis, as opposed to those in ambulatory surgery centers or 1099 contractual roles. Factors such as varying call coverage rotations, holiday differentials, and bonuses related to operational efficiency contribute to the wage differentials observed in the market. To maximize pay in Mount Pleasant, nurse anesthetists should consider leveraging opportunities within partnership-track CRNA-owned practices or exploring locum tenens positions that might offer higher flexibility and potential for increased income.
More salary data for Mount Pleasant, SC:
Frequently Asked Questions
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $219,656 for nurse anesthetistsin the Mount Pleasant metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Mount Pleasant is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov