Nurse Anesthetist Salary in Florence, SC: $221,108 (2026)
Quick Answer:A full-time nurse anesthetist in Florence, SC earns a median $221,108/year (≈ $106.30/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Florence's price level (8% below national, BEA RPP 91.5), that paycheck buys what $241,648 would nationally. Nominal pay sits 2.9% below the South Carolina state average.
Based on BLS state-level estimates · View source
In 2026, the nurse anesthetist salary in Florence, SC, is projected to reach a median of $221,108, which aligns closely with the regional market conditions. The salary for these professionals ranges from $141,628 at the 10th percentile to as high as $300,268 at the 90th percentile. These numbers, derived from state-level BLS data reflecting local cost of living adjustments, reveal significant disparities influenced by various factors, including call-coverage responsibilities, job settings, and regional demand for services. The distinct lifestyle and work-life balance associated with different employment scenarios can create substantial differences in remuneration within Florence's healthcare community.
About the Florence Market
Salary estimated from South Carolina average ($208,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $141,628 | $68.09 |
| Lower Range (P25) | $202,083 | $97.15 |
| Median (P50)(typical) | $221,108 | $106.30 |
| Upper Range (P75) | $267,325 | $128.52 |
| Top Earners (P90) | $300,268 | $144.36 |
Median Salary Position
11.16% below the national average
2026 Salary Percentile Distribution in Florence
In Florence, SC, the nurse anesthetist salary spread from the 10th to 90th percentile is $158,640 (2026 est.). At $221,108, the local median is 11.16% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Florence: You'd be above the median
How Florence Nurse Anesthetist Pay Compares
Florence median: $221,108/year (2026)
| Compared To | Median Salary | Florence Pays |
|---|---|---|
| South Carolina Average | $227,712 | -2.90% less |
| National Average | $248,893 | -11.16% less |
Nurse Anesthetists in Florence, SC earn a median of $221,108 per year (2026 est.), which is 11.16% lower than the national median of $248,893 and 2.90% below the South Carolina state average of $227,712.
Cost-of-Living Adjusted Salary
Florence has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Florence, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse anesthetist earning $221,108 nominally has purchasing power equivalent to $241,648 in an average-cost city — an effective 9.29% boost.
Compare Purchasing Power
Select a city to see how your salary compares after cost of living
Select a city above to compare purchasing power
2019 BLS Actual
$155,278
2025 BLS Actual
$210,179
2026 Current Est.
$221,108
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Florence (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $155,278 | Actual |
| 2020 | $163,087 | Actual |
| 2021 | $204,210 | Actual |
| 2022 | $205,590 | Actual |
| 2023 | $188,911 | Actual |
| 2024 | $184,780 | Actual |
| 2025 | $210,179 | Actual |
| 2026(current) | $221,108 | Estimated |
| 2027 | $232,606 | Projected |
Based on 7 years of BLS OEWS data for the Florence metropolitan area, the median nurse anesthetist salary grew 35.4% from $155,278 (2019) to $210,179 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $232,606 by 2027 — a total increase of $77,328 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Florence metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $141,628 – $202,083 |
| 3-5 years (Mid Career) | $202,083 – $221,108 |
| 5+ years (Experienced) | $221,108 – $267,325 |
| 10+ years (Top Earner) | $267,325 – $300,268 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Florence
With only nine nurse anesthetists currently practicing in the area, the job market remains relatively tight, presenting unique opportunities for those in the field. Florence's cost of living index stands at 91.5, suggesting that while salaries are lower than the national median, purchasing power remains relatively stable. Employers such as hospital systems and CRNA-owned anesthesia practices tend to offer higher compensation, particularly for those willing to engage in differentials for weekend and holiday shifts or participate in a partnership track. In this market, understanding the nuances of call rotation schedules and OR efficiency bonuses can be essential for maximizing earnings. For those pursuing a nurse anesthetist pay in Florence SC, it is advisable to consider positions with more favorable rotation patterns and additional stipends that accompany trauma center roles or specialties in chronic pain management, thereby enhancing overall compensation potential.
More salary data for Florence, SC:
Frequently Asked Questions
How much do nurse anesthetists make in Florence, SC in 2026?
Is Florence, SC a good place to work as a nurse anesthetist?
Can nurse anesthetists make $100K in Florence?
What is the cost-of-living adjusted nurse anesthetist salary in Florence?
How much does a nurse anesthetist make per hour in Florence?
Related Pages
Compare Salaries
Career Resources
Nearby Cities in South Carolina
Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $210,179 for nurse anesthetistsin the Florence metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Florence is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov