Nurse Anesthetists (CRNA) Salary

Florence vs North Charleston: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between Florence, SC and North Charleston, SC. All figures are 2026 estimates projected from BLS 2025 data.

Florence, SC
$221,108
$106.30/hr
North Charleston, SC
$245,765
$118.16/hr

Side-by-Side Comparison

MetricFlorence, SCNorth Charleston, SC
Median Salary$221,108$245,765
Hourly Rate$106.30$118.16
Entry Level (P10)$141,628$149,550
25th Percentile$202,083$219,674
75th Percentile$267,325$305,341
Top Earner (P90)$300,268$352,038
Total Employed922
Side-by-side bar chart comparing Florence ($221,108) and North Charleston ($245,765) nurse anesthetist salaries.FlorenceNorth CharlestonMedian Salary$221,108$245,765Entry Level (P10)$141,628$149,550Top Earner (P90)$300,268$352,038US Median $248,893

Verdict

North Charleston, SC offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Florence.

The salary gap between Florence and North Charleston is $24,657 (11.15%). North Charleston's median is -1.26% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Florence spans $158,640,North Charleston spans $202,488. North Charleston has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse anesthetists.

Florence
P10 (Entry)$141,628
P25$202,083
Median$221,108
P75$267,325
P90 (Top)$300,268
North Charleston
P10 (Entry)$149,550
P25$219,674
Median$245,765
P75$305,341
P90 (Top)$352,038

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, North Charleston ($268,596 effective) pays 11.15% more than Florence ($241,648 effective).

Florence
Nominal: $221,108
CoL Index: 91.5
Adjusted: $241,648
North Charleston
Nominal: $245,765
CoL Index: 91.5
Adjusted: $268,596

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Florence if…

  • You prefer the South Carolina area and lifestyle

Choose North Charleston if…

  • Higher median salary ($245,765/year)
  • Better top-earner potential ($352,038)
  • Larger job market (22 employed)
  • Better purchasing power (CoL-adjusted: $268,596)
  • You prefer the South Carolina area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Florence grew 2.9% from 2021 to 2025, compared to 19.0% growth in North Charleston over the same period.

Florence, SC

+2.9%

$204,210 (2021) → $210,179 (2025)

North Charleston, SC

+19.0%

$196,321 (2024) → $233,617 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: Florence or North Charleston?

North Charleston has a higher median nurse anesthetist salary at $245,765/year, compared to Florence at $221,108/year — a difference of $24,657 (11.15%).

What is the hourly rate difference between Florence and North Charleston?

Florence nurse anesthetists earn $106.30/hr while North Charleston hygienists earn $118.16/hr (2026 est.).

Should I relocate from Florence to North Charleston as a nurse anesthetist?

Consider more than just salary when comparing Florence and North Charleston. Factor in cost of living (CoL-adjusted: Florence = $241,648, North Charleston = $268,596), job availability (9 vs 22 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in Florence vs North Charleston?

Entry-level (10th percentile) nurse anesthetists earn $141,628 in Florence and $149,550 in North Charleston. The North Charleston area offers higher starting salaries.
AJ

Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov