Nurse Anesthetist Salary in Clemson, SC: $209,714 (2026)
Quick Answer:A full-time nurse anesthetist in Clemson, SC earns a median $209,714/year (≈ $100.82/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Clemson's price level (8% below national, BEA RPP 91.5), that paycheck buys what $229,196 would nationally. Nominal pay sits 7.9% below the South Carolina state average.
Based on BLS state-level estimates · View source

In Clemson, South Carolina, the projected median annual salary for nurse anesthetists stands at $209,714 for 2026, reflecting a significant opportunity for CRNAs within this market. This figure is approximately 15.74% lower than the national median of $248,893, indicating a distinctly different economic landscape for nurse anesthetist pay in Clemson, SC. The local salary range extends from $147,954 at the 10th percentile to $287,310 at the 90th percentile, highlighting the potential earnings variability based on experience, practice setting, and work responsibilities. These estimates, derived from 2025 BLS data, showcase how the regional cost of living and the job market's nature shape compensation for nurse anesthetists in this area.
About the Clemson Market
Salary estimated from South Carolina average ($208,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $147,954 | $71.14 |
| Lower Range (P25) | $189,180 | $90.96 |
| Median (P50)(typical) | $209,714 | $100.82 |
| Upper Range (P75) | $256,605 | $123.37 |
| Top Earners (P90) | $287,310 | $138.13 |
Median Salary Position
15.74% below the national average
2026 Salary Percentile Distribution in Clemson
In Clemson, SC, the nurse anesthetist salary spread from the 10th to 90th percentile is $139,356 (2026 est.). At $209,714, the local median is 15.74% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Clemson: You'd be in the lower-middle range
How Clemson Nurse Anesthetist Pay Compares
Clemson median: $209,714/year (2026)
| Compared To | Median Salary | Clemson Pays |
|---|---|---|
| South Carolina Average | $227,703 | -7.90% less |
| National Average | $248,893 | -15.74% less |
Nurse Anesthetists in Clemson, SC earn a median of $209,714 per year (2026 est.), which is 15.74% lower than the national median of $248,893 and 7.90% below the South Carolina state average of $227,703.
Cost-of-Living Adjusted Salary
Clemson has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Clemson, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse anesthetist earning $209,714 nominally has purchasing power equivalent to $229,196 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$147,276
2025 BLS Actual
$199,348
2026 Current Est.
$209,714
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Clemson (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $147,276 | Actual |
| 2020 | $154,682 | Actual |
| 2021 | $164,819 | Actual |
| 2022 | $171,121 | Actual |
| 2023 | $179,176 | Actual |
| 2024 | $175,258 | Actual |
| 2025 | $199,348 | Actual |
| 2026(current) | $209,714 | Estimated |
| 2027 | $220,619 | Projected |
Based on 7 years of BLS OEWS data for the Clemson metropolitan area, the median nurse anesthetist salary grew 35.4% from $147,276 (2019) to $199,348 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $220,619 by 2027 — a total increase of $73,343 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Clemson metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $147,954 – $189,180 |
| 3-5 years (Mid Career) | $189,180 – $209,714 |
| 5+ years (Experienced) | $209,714 – $256,605 |
| 10+ years (Top Earner) | $256,605 – $287,310 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Clemson
Examining the job market in Clemson reveals a relatively small workforce of just six employed nurse anesthetists, which could influence local pay dynamics amidst a cost of living index of 91.5—below the national average. A key factor in compensation differentiation is the type of employer; hospital systems tend to provide stable salaries and benefits, while CRNA-owned anesthesia practices may offer partnership tracks leading to increased earnings through profit distribution. Factors such as call coverage rotations, weekend differentials, and productivity bonuses further drive the disparity between lower and higher salaries. CRNAs seeking to maximize their earning potential should explore diverse practice settings, negotiate benefits, and consider being flexible with on-call responsibilities to leverage higher pay opportunities in Clemson, SC.
More salary data for Clemson, SC:
Frequently Asked Questions
How much do nurse anesthetists make in Clemson, SC in 2026?
Is Clemson, SC a good place to work as a nurse anesthetist?
Can nurse anesthetists make $100K in Clemson?
What is the cost-of-living adjusted nurse anesthetist salary in Clemson?
How much does a nurse anesthetist make per hour in Clemson?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $199,348 for nurse anesthetistsin the Clemson metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Clemson is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov