Clemson vs Columbia: Nurse Anesthetist Salary (2026)
Compare nurse anesthetist salaries between Clemson, SC and Columbia, SC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Clemson, SC | Columbia, SC |
|---|---|---|
| Median Salary | $209,714 | $285,460▲ |
| Hourly Rate | $100.82 | $137.24▲ |
| Entry Level (P10) | $147,954 | $225,128▲ |
| 25th Percentile | $189,180 | $235,985▲ |
| 75th Percentile | $256,605 | $302,639▲ |
| Top Earner (P90) | $287,310 | $350,348▲ |
| Total Employed | 6 | 210▲ |
Verdict
Columbia, SC offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Clemson.
The salary gap between Clemson and Columbia is $75,746 (36.12%). Columbia's median is +14.69% compared to the US national median of $248,893.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Clemson spans $139,356,Columbia spans $125,220. Clemson has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Columbia ($304,777 effective) pays 32.98% more than Clemson ($229,196 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Clemson if…
- ✓You prefer the South Carolina area and lifestyle
Choose Columbia if…
- ✓Higher median salary ($285,460/year)
- ✓Better top-earner potential ($350,348)
- ✓Larger job market (210 employed)
- ✓Better purchasing power (CoL-adjusted: $304,777)
- ✓You prefer the South Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Clemson grew 13.7% from 2024 to 2025, compared to 51.1% growth in Columbia over the same period.
Clemson, SC
$175,258 (2024) → $199,348 (2025)
Columbia, SC
$179,550 (2019) → $271,350 (2025)
View Full Salary Data
Clemson, SC
Columbia, SC
Frequently Asked Questions
Which city pays nurse anesthetists more: Clemson or Columbia?
What is the hourly rate difference between Clemson and Columbia?
Should I relocate from Clemson to Columbia as a nurse anesthetist?
What do entry-level nurse anesthetists earn in Clemson vs Columbia?
Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov