Nurse Anesthetist Salary in Cape Girardeau, MO: $216,344 (2026)
Quick Answer:A full-time nurse anesthetist in Cape Girardeau, MO earns a median $216,344/year (≈ $104.01/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Cape Girardeau's price level (10% below national, BEA RPP 89.6), that paycheck buys what $241,455 would nationally. Nominal pay sits 3.0% below the Missouri state average.
Based on BLS state-level estimates · View source

In Cape Girardeau, Missouri, the projected nurse anesthetist salary in 2026 is $216,344, reflecting a competitive niche within the healthcare field. This figure is significantly lower than the national median of $248,893, indicating a slight disparity that job seekers should consider. The salary range varies widely, from $155,219 at the 10th percentile to $293,462 at the 90th percentile, revealing opportunities for both entry-level and highly experienced professionals. These estimates are informed by 2025 BLS OEWS data, projected to 2026, incorporating local adjustments for cost of living. Cape Girardeau’s workforce consists of only six nurse anesthetists, suggesting a close-knit market where competition for desirable positions, particularly those in hospital systems, can be intense.
About the Cape Girardeau Market
Salary estimated from Missouri average ($215,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $155,219 | $74.63 |
| Lower Range (P25) | $197,518 | $94.96 |
| Median (P50)(typical) | $216,344 | $104.01 |
| Upper Range (P75) | $261,360 | $125.65 |
| Top Earners (P90) | $293,462 | $141.08 |
Median Salary Position
13.08% below the national average
2026 Salary Percentile Distribution in Cape Girardeau
In Cape Girardeau, MO, the nurse anesthetist salary spread from the 10th to 90th percentile is $138,243 (2026 est.). At $216,344, the local median is 13.08% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Cape Girardeau: You'd be in the lower-middle range
How Cape Girardeau Nurse Anesthetist Pay Compares
Cape Girardeau median: $216,344/year (2026)
| Compared To | Median Salary | Cape Girardeau Pays |
|---|---|---|
| Missouri Average | $223,035 | -3.00% less |
| National Average | $248,893 | -13.08% less |
Nurse Anesthetists in Cape Girardeau, MO earn a median of $216,344 per year (2026 est.), which is 13.08% lower than the national median of $248,893 and 3.00% below the Missouri state average of $223,035.
Cost-of-Living Adjusted Salary
Cape Girardeau has a cost of living 10.40% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Cape Girardeau, MO has a cost-of-living index of 89.6 (below the national average of 100). A nurse anesthetist earning $216,344 nominally has purchasing power equivalent to $241,455 in an average-cost city — an effective 11.61% boost.
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2019 BLS Actual
$151,932
2025 BLS Actual
$205,650
2026 Current Est.
$216,344
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Cape Girardeau (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $151,932 | Actual |
| 2020 | $159,572 | Actual |
| 2021 | $170,029 | Actual |
| 2022 | $176,531 | Actual |
| 2023 | $184,841 | Actual |
| 2024 | $186,883 | Actual |
| 2025 | $205,650 | Actual |
| 2026(current) | $216,344 | Estimated |
| 2027 | $227,594 | Projected |
Based on 7 years of BLS OEWS data for the Cape Girardeau metropolitan area, the median nurse anesthetist salary grew 35.4% from $151,932 (2019) to $205,650 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $227,594 by 2027 — a total increase of $75,662 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Cape Girardeau metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $155,219 – $197,518 |
| 3-5 years (Mid Career) | $197,518 – $216,344 |
| 5+ years (Experienced) | $216,344 – $261,360 |
| 10+ years (Top Earner) | $261,360 – $293,462 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Cape Girardeau
The local job market reflects a mix of employers that can influence nurse anesthetist pay in Cape Girardeau, MO. These include hospital systems, ambulatory surgery centers, and CRNA-owned practices, each offering distinct compensation structures, whether through W-2 employment or 1099 contracts. With a cost of living index at 89.6, the purchasing power for nurse anesthetists is enhanced, although salaries remain below the national average. Variations in pay stem from factors such as call coverage rotations, weekend and holiday differentials, and the efficiency of operating room practices. For those seeking to maximize their earnings, joining a CRNA-owned group practice with partnership opportunities can be advantageous, especially where profit distribution models favor high-performing providers. Understanding the local landscape, including the pros and cons of working in military treatment facilities or locum tenens arrangements, can significantly impact how much do nurse anesthetists make in Cape Girardeau.
More salary data for Cape Girardeau, MO:
Frequently Asked Questions
How much do nurse anesthetists make in Cape Girardeau, MO in 2026?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $205,650 for nurse anesthetistsin the Cape Girardeau metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Cape Girardeau is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov