Cape Girardeau vs Columbia: Nurse Anesthetist Salary (2026)
Compare nurse anesthetist salaries between Cape Girardeau, MO and Columbia, MO. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Cape Girardeau, MO | Columbia, MO |
|---|---|---|
| Median Salary | $216,344 | $326,299▲ |
| Hourly Rate | $104.01 | $156.87▲ |
| Entry Level (P10) | $155,219 | $226,622▲ |
| 25th Percentile | $197,518 | $257,729▲ |
| 75th Percentile | $261,360 | $326,299▲ |
| Top Earner (P90) | $293,462 | $326,299▲ |
| Total Employed | 6 | 90▲ |
Verdict
Columbia, MO offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Cape Girardeau.
The salary gap between Cape Girardeau and Columbia is $109,955 (50.82%). Columbia's median is +31.10% compared to the US national median of $248,893.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Cape Girardeau spans $138,243,Columbia spans $99,677. Cape Girardeau has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Columbia ($364,833 effective) pays 51.10% more than Cape Girardeau ($241,455 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Cape Girardeau if…
- ✓You prefer the Missouri area and lifestyle
Choose Columbia if…
- ✓Higher median salary ($326,299/year)
- ✓Better top-earner potential ($326,299)
- ✓Larger job market (90 employed)
- ✓Better purchasing power (CoL-adjusted: $364,833)
- ✓You prefer the Missouri area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Cape Girardeau grew 10.0% from 2024 to 2025, compared to 79.8% growth in Columbia over the same period.
Cape Girardeau, MO
$186,883 (2024) → $205,650 (2025)
Columbia, MO
$172,490 (2019) → $310,170 (2025)
View Full Salary Data
Cape Girardeau, MO
Columbia, MO
Frequently Asked Questions
Which city pays nurse anesthetists more: Cape Girardeau or Columbia?
What is the hourly rate difference between Cape Girardeau and Columbia?
Should I relocate from Cape Girardeau to Columbia as a nurse anesthetist?
What do entry-level nurse anesthetists earn in Cape Girardeau vs Columbia?
Related Comparisons
Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov