Nurse Anesthetist Salary in Palmdale, CA: $279,707 (2026)
Quick Answer:A full-time nurse anesthetist in Palmdale, CA earns a median $279,707/year (≈ $134.48/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Palmdale's price level (13% above national, BEA RPP 113.1), that paycheck buys what $247,309 would nationally. Nominal pay sits 0.6% below the California state average.
Based on BLS state-level estimates · View source

In 2026, the median annual salary for nurse anesthetists in Palmdale, California, is projected to reach $279,707, placing it 12.38% higher than the national median of $248,893. The range for salaries in this market varies significantly, with the lowest 10% earning approximately $184,525 and the top 90% earning up to $417,456. These estimates, derived from BLS state-level data and adjusted for regional cost of living, illustrate the competitive positioning of nurse anesthetist pay in Palmdale. This compensation profile reflects the dynamics of the Anesthesia Care Team model prevalent in California, where CRNAs work alongside anesthesiologists and have an integral role in patient management.
About the Palmdale Market
Salary estimated from California average ($260,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $184,525 | $88.72 |
| Lower Range (P25) | $243,605 | $117.12 |
| Median (P50)(typical) | $279,707 | $134.48 |
| Upper Range (P75) | $358,025 | $172.13 |
| Top Earners (P90) | $417,456 | $200.70 |
Median Salary Position
12.38% above the national average
2026 Salary Percentile Distribution in Palmdale
In Palmdale, CA, the nurse anesthetist salary spread from the 10th to 90th percentile is $232,931 (2026 est.). At $279,707, the local median is 12.38% above the national median of $248,893.
Salary Calculator
At 40 hours/week in Palmdale: You'd be in the lower-middle range
How Palmdale Nurse Anesthetist Pay Compares
Palmdale median: $279,707/year (2026)
| Compared To | Median Salary | Palmdale Pays |
|---|---|---|
| California Average | $281,395 | -0.60% less |
| National Average | $248,893 | +12.38% more |
Nurse Anesthetists in Palmdale, CA earn a median of $279,707 per year (2026 est.), which is 12.38% higher than the national median of $248,893 and 0.60% below the California state average of $281,395.
Cost-of-Living Adjusted Salary
Palmdale has a cost of living 13.10% above the national average.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Palmdale, CA has a cost-of-living index of 113.1 (above the national average of 100). While the nominal salary of $279,707 is competitive, the higher cost of living reduces purchasing power to an effective $247,309 — a 11.58% reduction.
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2019 BLS Actual
$196,430
2025 BLS Actual
$265,881
2026 Current Est.
$279,707
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Palmdale (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $196,430 | Actual |
| 2020 | $206,308 | Actual |
| 2021 | $219,827 | Actual |
| 2022 | $228,234 | Actual |
| 2023 | $238,977 | Actual |
| 2024 | $292,189 | Actual |
| 2025 | $265,881 | Actual |
| 2026(current) | $279,707 | Estimated |
| 2027 | $294,252 | Projected |
Based on 7 years of BLS OEWS data for the Palmdale metropolitan area, the median nurse anesthetist salary grew 35.4% from $196,430 (2019) to $265,881 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $294,252 by 2027 — a total increase of $97,822 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Palmdale metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $184,525 – $243,605 |
| 3-5 years (Mid Career) | $243,605 – $279,707 |
| 5+ years (Experienced) | $279,707 – $358,025 |
| 10+ years (Top Earner) | $358,025 – $417,456 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Palmdale
Palmdale's job market currently employs 29 nurse anesthetists, highlighting a community of professionals dedicated to advanced pain management. With a cost-of-living index of 113.1, living expenses in the area exceed the national average, impacting the real purchasing power of salaries. Among local employers, hospital systems tend to offer more stable W-2 positions, while ambulatory surgery centers may provide competitive opportunities through either W-2 or 1099 arrangements. The variation in pay can be attributed to factors such as call coverage arrangements and weekend differentials. For CRNAs aiming to maximize their earnings, pursuing high-traffic specialty areas or consulting for locum tenens agencies can enhance income potential, given the ongoing demand for flexibility and expertise in diverse settings.
More salary data for Palmdale, CA:
Frequently Asked Questions
How much do nurse anesthetists make in Palmdale, CA in 2026?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $265,881 for nurse anesthetistsin the Palmdale metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Palmdale is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov