Greenville vs North Charleston: Nurse Anesthetist Salary (2026)
Compare nurse anesthetist salaries between Greenville, SC and North Charleston, SC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Greenville, SC | North Charleston, SC |
|---|---|---|
| Median Salary | $241,686 | $245,765▲ |
| Hourly Rate | $116.19 | $118.16▲ |
| Entry Level (P10) | $196,040▲ | $149,550 |
| 25th Percentile | $241,055▲ | $219,674 |
| 75th Percentile | $303,460 | $305,341▲ |
| Top Earner (P90) | $451,329▲ | $352,038 |
| Total Employed | N/A | 22 |
Verdict
North Charleston, SC offers better overall compensation for nurse anesthetists, winning 3 out of 4 metrics compared to Greenville.
The salary gap between Greenville and North Charleston is $4,079 (1.69%). North Charleston's median is -1.26% compared to the US national median of $248,893.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Greenville spans $255,289,North Charleston spans $202,488. Greenville has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, North Charleston ($268,596 effective) pays 3.64% more than Greenville ($259,153 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Greenville if…
- ✓Better top-earner potential ($451,329)
- ✓You prefer the South Carolina area and lifestyle
Choose North Charleston if…
- ✓Higher median salary ($245,765/year)
- ✓Larger job market (22 employed)
- ✓Better purchasing power (CoL-adjusted: $268,596)
- ✓You prefer the South Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Greenville grew 21.2% from 2019 to 2025, compared to 19.0% growth in North Charleston over the same period.
Greenville, SC
$189,510 (2019) → $229,740 (2025)
North Charleston, SC
$196,321 (2024) → $233,617 (2025)
View Full Salary Data
Greenville, SC
North Charleston, SC
Frequently Asked Questions
Which city pays nurse anesthetists more: Greenville or North Charleston?
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Should I relocate from Greenville to North Charleston as a nurse anesthetist?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov