Senior Nurse Anesthetist Salary in Winston-Salem, NC: $357,246 (2026)
Quick Answer:The top tier of nurse anesthetists working in Winston-Salem, NC — those at or above the 90th percentile — pull in $357,246/year or more for 2026, based on BLS OEWS 2025 estimates for SOC 29-1151. Strip back Winston-Salem's price premium (BEA RPP 93.6, 6% below national) and that top-decile pay carries the same buying power as $381,673 in average-cost America. The 48% spread above city median typically rewards 7+ years of practice or specialty credentials.
Based on BLS state-level estimates · View source

Senior nurse anesthetists in Winston-Salem, North Carolina, can anticipate a competitive compensation structure as they navigate their advanced careers. With a projected median annual salary of $241,203 for 2026, these professionals can aspire to significantly higher earnings through specialized skills and extensive experience. The top 10% of earners in this field can expect salaries as high as $357,246, creating a pronounced gap over the median figure. Achieving such impressive pay requires not only clinical expertise but also a strategic focus on areas like pediatric and cardiac anesthesia, as well as advanced leadership roles within established healthcare institutions. The income potential in this market not only reflects the demand for quality anesthesia care but also emphasizes the importance of continuous professional development as CRNAs aim for senior-level roles.
About the Winston-Salem Market
Salary estimated from North Carolina average ($210,000) adjusted for local cost of living.
2026 Salary Percentile Distribution in Winston-Salem
Experienced nurse anesthetists at the top of the pay scale in Winston-Salem earn between $304,973 and $357,246 per year (2026 est.). This $212,578 range from 10th to 90th percentile reflects significant earnings potential growth over a career. The Winston-Salem median of $241,203 sits 3.09% below the US median.
Top CRNA Salary Comparison
| Level | Winston-Salem | National |
|---|---|---|
| Median (P50) | $241,203 | $248,893 |
| 75th Percentile | $304,973 | $309,656 |
| 90th Percentile (Top 10%) | $357,246 | $357,154 |
In Winston-Salem, experienced nurse anesthetists (P90) earn 48.11% more than the local median — reflecting the significant value of specialization and tenure in this market.
What Drives Top Nurse Anesthetist Pay in Winston-Salem
Advanced Certifications in North Carolina
NC nurse anesthetists with additional specialty certifications within the nursing field earn significantly above the $241,203 median. Expanded-scope credentials are increasingly valued by Winston-Salem employers.
Specialty Focus
Nurse Anesthetists focusing on high-acuity or specialty areas within the nursing field in Winston-Salem command premium compensation, often reaching the $304,973–$357,246 range.
Large Health-System & Multi-Site Experience
Large hospital systems and multi-site employers in the Winston-Salem metro area often pay above-market rates for experienced nurse anesthetists who demonstrate efficiency and leadership.
Employer Loyalty & Patient Relationships
Long-tenured nurse anesthetists in Winston-Salem with established relationships have strong negotiating leverage. In this developing market, retention bonuses and annual raises are common for top performers.
Continuing Education & Leadership
Nurse Anesthetists in North Carolina who pursue advanced degrees, mentor junior staff, or lead clinical education programs position themselves for the highest compensation tiers and management roles.
Nurse Anesthetist Career & Wage Growth Path in Winston-Salem
Clinical Nurse Anesthetist
0-5 yearsSenior/Lead Nurse Anesthetist
5-10 yearsNurse Anesthetist Department Manager
10+ yearsEducator / Specialty Leadership
AdvancedWinston-Salem ranks #5 of 44 North Carolina cities for top earner nurse anesthetist salary (90th percentile: $357,246).
Top 10% nurse anesthetist compensation in Winston-Salem ($357,246) is 6.68% above the North Carolina average P90 ($334,874).
2024 BLS Actual
$267,201
2025 BLS Actual
$339,587
2026 Current Est.
$357,246
2024–2027 Growth
+40.7%
Salary Trajectory for Nurse Anesthetists in Winston-Salem (2024–2027)
2024–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2024 | $267,201 | Actual |
| 2025 | $339,587 | Actual |
| 2026(current) | $357,246 | Estimated |
| 2027 | $375,822 | Projected |
Top-earning nurse anesthetists (90th percentile) in Winston-Salem saw their compensation grow 27.1% from $267,201 in 2024 to $339,587 in 2025, based on 2 years of BLS OEWS data for this metropolitan area. At a 5.20% annual growth rate, senior-level pay is projected to reach $375,822 by 2027, reflecting continued demand for clinical expertise and expanded-function credentials.
Note: Historical values (2024–2025) are actual BLS OEWS figures for the Winston-Salem metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 2-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Maximizing Your Nurse Anesthetist Earnings in Winston-Salem
In Winston-Salem, various specialties command higher pay rates, particularly pediatric anesthesia, cardiac anesthesia, and OB/obstetric anesthesia, with seasoned nurse anesthetists often earning elevated wages due to their skills in critical care scenarios. Differences in compensation are prevalent depending on employer types. For instance, CRNAs working within hospital systems typically enjoy W-2 employment benefits, whereas those in ambulatory surgery centers might choose between W-2 or 1099 options, affecting their overall take-home pay. Additional earnings can also stem from leadership positions such as chief CRNA or anesthesia department director, both of which offer pathways to substantial income growth. Certification from the NBCRNA and advanced education like the DNP or DNAP can also enhance salary prospects in NC. Moreover, non-salary incentives, including call coverage rotation and trauma center stipends, play a significant role in total compensation, reflecting the multifaceted nature of the senior nurse anesthetist pay spectrum in Winston-Salem.
More salary data for Winston-Salem, NC:
Frequently Asked Questions
How much do experienced nurse anesthetists make in Winston-Salem in 2026?
What drives higher nurse anesthetist pay in Winston-Salem?
What certifications boost nurse anesthetist salary in Winston-Salem?
Can experienced nurse anesthetists make six figures in Winston-Salem?
How much does nurse anesthetist salary increase over time in Winston-Salem?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Top-earner salary figures on this page are 2026 projections derived from the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. BLS reported a 90th percentile salary of $339,587 for nurse anesthetists in the Winston-Salem metro area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 senior-level compensation. Individual earnings depend on certifications, specialization, practice type, and years of clinical experience.
Data Sources & Methodology
Salary data for Winston-Salem is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov