Nurse Anesthetist Salary in Sioux Falls, SD: $256,225 (2026)
Quick Answer:A full-time nurse anesthetist in Sioux Falls, SD earns a median $256,225/year (≈ $123.19/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Sioux Falls's price level (9% below national, BEA RPP 90.6), that paycheck buys what $282,712 would nationally. Nominal pay sits 10.9% above the South Dakota state average.
Official BLS data · View source

In Sioux Falls, South Dakota, the nurse anesthetist salary for 2026 is projected to be $256,225, placing local compensation slightly above the national median of $248,893. This robust figure reflects a salary range that varies significantly, from $204,298 at the 10th percentile to $381,497 at the 90th percentile, highlighting opportunities for both entry-level and experienced practitioners. These insights come from the Bureau of Labor Statistics' Occupational Employment and Wage Statistics, which indicate a strong earning potential for nurse anesthetists in an environment supportive of CRNA autonomy, particularly advantageous in the context of South Dakota's practice regulations.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $204,298 | $98.21 |
| Lower Range (P25) | $204,298 | $98.21 |
| Median (P50)(typical) | $256,225 | $123.19 |
| Upper Range (P75) | $283,493 | $136.30 |
| Top Earners (P90) | $381,497 | $183.42 |
Median Salary Position
2.95% above the national average
2026 Salary Percentile Distribution in Sioux Falls
In Sioux Falls, SD, the nurse anesthetist salary spread from the 10th to 90th percentile is $177,199 (2026 est.). At $256,225, the local median is 2.95% above the national median of $248,893.
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At 40 hours/week in Sioux Falls: You'd be in the lower-middle range
How Sioux Falls Nurse Anesthetist Pay Compares
Sioux Falls median: $256,225/year (2026)
| Compared To | Median Salary | Sioux Falls Pays |
|---|---|---|
| South Dakota Average | $231,042 | +10.90% more |
| National Average | $248,893 | +2.95% more |
Nurse Anesthetists in Sioux Falls, SD earn a median of $256,225 per year (2026 est.), which is 2.95% higher than the national median of $248,893 and 10.90% above the South Dakota state average of $231,042.
Cost-of-Living Adjusted Salary
Sioux Falls has a cost of living 9.37% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Sioux Falls, SD has a cost-of-living index of 90.631 (below the national average of 100). A nurse anesthetist earning $256,225 nominally has purchasing power equivalent to $282,712 in an average-cost city — an effective 10.34% boost.
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2019 BLS Actual
$190,460
2025 BLS Actual
$243,560
2026 Current Est.
$256,225
2019–2027 Growth
+41.5%
Salary Trajectory for Nurse Anesthetists in Sioux Falls (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $190,460 | Actual |
| 2020 | $194,750 | Actual |
| 2021 | $165,900 | Actual |
| 2022 | $184,880 | Actual |
| 2023 | $199,690 | Actual |
| 2024 | $221,020 | Actual |
| 2025 | $243,560 | Actual |
| 2026(current) | $256,225 | Estimated |
| 2027 | $269,549 | Projected |
Based on 7 years of BLS OEWS data for the Sioux Falls metropolitan area, the median nurse anesthetist salary grew 27.9% from $190,460 (2019) to $243,560 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $269,549 by 2027 — a total increase of $79,089 (41.53%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Sioux Falls metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $204,298 – $204,298 |
| 3-5 years (Mid Career) | $204,298 – $256,225 |
| 5+ years (Experienced) | $256,225 – $283,493 |
| 10+ years (Top Earner) | $283,493 – $381,497 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Sioux Falls
With approximately 230 nurse anesthetists employed in the Sioux Falls market, there is a healthy demand for these professionals. The area's cost of living index, at 90.631, suggests that residents can enjoy a more favorable purchasing power compared to many other regions. Major employers such as local hospital systems and ambulatory surgery centers tend to offer competitive pay, yet those in private practice or CRNA-owned anesthesia groups may find lucrative partnership opportunities that significantly enhance earnings potential. Differences in compensation can also emerge from factors like call coverage rotations and additional stipends for high-demand cases, which create variations in pay. To maximize financial outcomes, nurse anesthetists should strategically consider locations with favorable working conditions and negotiate incentives tied to their experience and the specific demands of their roles in Sioux Falls SD.
More salary data for Sioux Falls, SD:
Frequently Asked Questions
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $243,560 for nurse anesthetistsin the Sioux Falls metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov