Nurse Anesthetist Salary in Spartanburg, SC: $221,020 (2026)
Quick Answer:A full-time nurse anesthetist in Spartanburg, SC earns a median $221,020/year (≈ $106.26/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Spartanburg's price level (8% below national, BEA RPP 91.5), that paycheck buys what $241,552 would nationally. Nominal pay sits 2.9% below the South Carolina state average.
Based on BLS state-level estimates · View source
In 2026, nurse anesthetists in Spartanburg, South Carolina, can expect a median annual salary of $221,020, placing their compensation notably lower than the national median of $248,893. The expected salary range in this market varies from $141,425 at the 10th percentile to $299,428 at the 90th percentile, illustrating a diverse pay scale. These estimates come from BLS state-level data and incorporate regional cost adjustments, offering a clearer picture of earnings potential in Spartanburg. This relatively modest salary figure reflects local market conditions under the Anesthesia Care Team (ACT) model, which is prevalent in South Carolina, hinting at opportunities for CRNAs to maximize their earnings depending on their employment settings.
About the Spartanburg Market
Salary estimated from South Carolina average ($208,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $141,425 | $67.99 |
| Lower Range (P25) | $201,895 | $97.07 |
| Median (P50)(typical) | $221,020 | $106.26 |
| Upper Range (P75) | $267,448 | $128.59 |
| Top Earners (P90) | $299,428 | $143.96 |
Median Salary Position
11.2% below the national average
2026 Salary Percentile Distribution in Spartanburg
In Spartanburg, SC, the nurse anesthetist salary spread from the 10th to 90th percentile is $158,003 (2026 est.). At $221,020, the local median is 11.2% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Spartanburg: You'd be above the median
How Spartanburg Nurse Anesthetist Pay Compares
Spartanburg median: $221,020/year (2026)
| Compared To | Median Salary | Spartanburg Pays |
|---|---|---|
| South Carolina Average | $227,621 | -2.90% less |
| National Average | $248,893 | -11.20% less |
Nurse Anesthetists in Spartanburg, SC earn a median of $221,020 per year (2026 est.), which is 11.20% lower than the national median of $248,893 and 2.90% below the South Carolina state average of $227,621.
Cost-of-Living Adjusted Salary
Spartanburg has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Spartanburg, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse anesthetist earning $221,020 nominally has purchasing power equivalent to $241,552 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$155,216
2025 BLS Actual
$210,095
2026 Current Est.
$221,020
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Spartanburg (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $155,216 | Actual |
| 2020 | $163,021 | Actual |
| 2021 | $173,704 | Actual |
| 2022 | $180,347 | Actual |
| 2023 | $188,836 | Actual |
| 2024 | $225,420 | Actual |
| 2025 | $210,095 | Actual |
| 2026(current) | $221,020 | Estimated |
| 2027 | $232,513 | Projected |
Based on 7 years of BLS OEWS data for the Spartanburg metropolitan area, the median nurse anesthetist salary grew 35.4% from $155,216 (2019) to $210,095 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $232,513 by 2027 — a total increase of $77,297 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Spartanburg metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $141,425 – $201,895 |
| 3-5 years (Mid Career) | $201,895 – $221,020 |
| 5+ years (Experienced) | $221,020 – $267,448 |
| 10+ years (Top Earner) | $267,448 – $299,428 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Spartanburg
With only seven nurse anesthetists currently employed in the area, the local job market is rather limited, impacting both competition and pay levels. The cost of living index in Spartanburg stands at 91.5, indicating that living expenses are below the national average, which may stretch take-home pay further. Major employers in the region include hospital systems, ambulatory surgery centers, and locally owned anesthesia group practices that may offer higher compensation through profit-sharing arrangements for those on partnership tracks. The variability in earnings often stems from factors such as on-call coverage ratios, weekend and holiday differentials, and bonuses linked to operational efficiency. For those looking to enhance their nurse anesthetist pay in Spartanburg, understanding these dynamics while actively seeking roles that offer higher stipends or incentives can prove beneficial.
More salary data for Spartanburg, SC:
Frequently Asked Questions
How much do nurse anesthetists make in Spartanburg, SC in 2026?
Is Spartanburg, SC a good place to work as a nurse anesthetist?
Can nurse anesthetists make $100K in Spartanburg?
What is the cost-of-living adjusted nurse anesthetist salary in Spartanburg?
How much does a nurse anesthetist make per hour in Spartanburg?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $210,095 for nurse anesthetistsin the Spartanburg metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Spartanburg is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov