Nurse Anesthetist Salary in Simpsonville, SC: $219,305 (2026)
Quick Answer:A full-time nurse anesthetist in Simpsonville, SC earns a median $219,305/year (≈ $105.43/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Simpsonville's price level (8% below national, BEA RPP 91.5), that paycheck buys what $239,678 would nationally. Nominal pay sits 3.7% below the South Carolina state average.
Based on BLS state-level estimates · View source

In Simpsonville, SC, the 2026 median annual nurse anesthetist salary is projected at $219,305, reflecting a localized market influenced by various factors such as call coverage and lifestyle choices. The salary spectrum extends from $153,496 at the 10th percentile to $297,777 at the 90th percentile, indicating a significant variability based on experience, employer, and job responsibilities. Estimates derived from 2025 BLS data and regional cost adjustments suggest that while compensation may lag behind the national median salary of $248,893 by approximately 11.89%, the local market offers unique opportunities that may contribute to job satisfaction and work-life balance.
About the Simpsonville Market
Salary estimated from South Carolina average ($208,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $153,496 | $73.80 |
| Lower Range (P25) | $196,421 | $94.44 |
| Median (P50)(typical) | $219,305 | $105.43 |
| Upper Range (P75) | $267,176 | $128.45 |
| Top Earners (P90) | $297,777 | $143.17 |
Median Salary Position
11.89% below the national average
2026 Salary Percentile Distribution in Simpsonville
In Simpsonville, SC, the nurse anesthetist salary spread from the 10th to 90th percentile is $144,281 (2026 est.). At $219,305, the local median is 11.89% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Simpsonville: You'd be in the lower-middle range
How Simpsonville Nurse Anesthetist Pay Compares
Simpsonville median: $219,305/year (2026)
| Compared To | Median Salary | Simpsonville Pays |
|---|---|---|
| South Carolina Average | $227,731 | -3.70% less |
| National Average | $248,893 | -11.89% less |
Nurse Anesthetists in Simpsonville, SC earn a median of $219,305 per year (2026 est.), which is 11.89% lower than the national median of $248,893 and 3.70% below the South Carolina state average of $227,731.
Cost-of-Living Adjusted Salary
Simpsonville has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Simpsonville, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse anesthetist earning $219,305 nominally has purchasing power equivalent to $239,678 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$154,012
2025 BLS Actual
$208,465
2026 Current Est.
$219,305
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Simpsonville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $154,012 | Actual |
| 2020 | $161,757 | Actual |
| 2021 | $172,357 | Actual |
| 2022 | $178,947 | Actual |
| 2023 | $187,371 | Actual |
| 2024 | $183,273 | Actual |
| 2025 | $208,465 | Actual |
| 2026(current) | $219,305 | Estimated |
| 2027 | $230,709 | Projected |
Based on 7 years of BLS OEWS data for the Simpsonville metropolitan area, the median nurse anesthetist salary grew 35.4% from $154,012 (2019) to $208,465 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $230,709 by 2027 — a total increase of $76,697 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Simpsonville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $153,496 – $196,421 |
| 3-5 years (Mid Career) | $196,421 – $219,305 |
| 5+ years (Experienced) | $219,305 – $267,176 |
| 10+ years (Top Earner) | $267,176 – $297,777 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Simpsonville
With only five nurse anesthetists actively working in the Simpsonville area, the job market appears stable, providing a closer-knit professional community. The local cost of living index stands at 91.5, which may enhance the purchasing power of nurse anesthetist pay in Simpsonville, SC. Employers such as hospital systems and ambulatory surgery centers typically offer higher salaries, but nuances in pay structures between W-2 positions and partnerships in CRNA-owned practices will influence earnings. The wide gap in compensation can often be linked to varying call coverage requirements, such as a 1-in-5 rotation versus a 1-in-8, along with additional pay elements like weekend differentials and performance bonuses. To maximize income, prospective nurse anesthetists should prioritize negotiating for advantageous contracts and consider diverse employment settings, as well as strategically leveraging their skills within this evolving market.
More salary data for Simpsonville, SC:
Frequently Asked Questions
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Can nurse anesthetists make $100K in Simpsonville?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $208,465 for nurse anesthetistsin the Simpsonville metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Simpsonville is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov