Nurse Anesthetist Salary in Jefferson City, MO: $212,450 (2026)
Quick Answer:A full-time nurse anesthetist in Jefferson City, MO earns a median $212,450/year (≈ $102.14/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Jefferson City's price level (10% below national, BEA RPP 89.6), that paycheck buys what $237,109 would nationally. Nominal pay sits 4.7% below the Missouri state average.
Based on BLS state-level estimates · View source

In Jefferson City, Missouri, the projected nurse anesthetist salary in 2026 is $212,450, marking a relative decrease compared to the national median of $248,893. This local figure falls within a substantial salary range, with the bottom 10% earning approximately $146,119 and the top 10% making around $301,370. These figures reflect the interplay between call-coverage duties and lifestyle choices that many nurse anesthetists must navigate. Factors such as work hours, weekend rotations, and the specific demands of local employers contribute to the variation in wages across this range. Based on 2025 BLS data, projected to 2026, these estimates underscore the importance of understanding the local job market dynamics for nurse anesthetists in Jefferson City.
About the Jefferson City Market
Salary estimated from Missouri average ($215,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $146,119 | $70.25 |
| Lower Range (P25) | $189,304 | $91.01 |
| Median (P50)(typical) | $212,450 | $102.14 |
| Upper Range (P75) | $264,691 | $127.25 |
| Top Earners (P90) | $301,370 | $144.89 |
Median Salary Position
14.64% below the national average
2026 Salary Percentile Distribution in Jefferson City
In Jefferson City, MO, the nurse anesthetist salary spread from the 10th to 90th percentile is $155,251 (2026 est.). At $212,450, the local median is 14.64% below the national median of $248,893.
Salary Calculator
At 40 hours/week in Jefferson City: You'd be in the lower-middle range
How Jefferson City Nurse Anesthetist Pay Compares
Jefferson City median: $212,450/year (2026)
| Compared To | Median Salary | Jefferson City Pays |
|---|---|---|
| Missouri Average | $222,928 | -4.70% less |
| National Average | $248,893 | -14.64% less |
Nurse Anesthetists in Jefferson City, MO earn a median of $212,450 per year (2026 est.), which is 14.64% lower than the national median of $248,893 and 4.70% below the Missouri state average of $222,928.
Cost-of-Living Adjusted Salary
Jefferson City has a cost of living 10.40% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Jefferson City, MO has a cost-of-living index of 89.6 (below the national average of 100). A nurse anesthetist earning $212,450 nominally has purchasing power equivalent to $237,109 in an average-cost city — an effective 11.61% boost.
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2019 BLS Actual
$149,198
2025 BLS Actual
$201,949
2026 Current Est.
$212,450
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Jefferson City (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $149,198 | Actual |
| 2020 | $156,701 | Actual |
| 2021 | $166,969 | Actual |
| 2022 | $173,354 | Actual |
| 2023 | $181,514 | Actual |
| 2024 | $183,520 | Actual |
| 2025 | $201,949 | Actual |
| 2026(current) | $212,450 | Estimated |
| 2027 | $223,498 | Projected |
Based on 7 years of BLS OEWS data for the Jefferson City metropolitan area, the median nurse anesthetist salary grew 35.4% from $149,198 (2019) to $201,949 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $223,498 by 2027 — a total increase of $74,300 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Jefferson City metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $146,119 – $189,304 |
| 3-5 years (Mid Career) | $189,304 – $212,450 |
| 5+ years (Experienced) | $212,450 – $264,691 |
| 10+ years (Top Earner) | $264,691 – $301,370 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Jefferson City
The job market for nurse anesthetists in Jefferson City includes approximately eight professionals currently employed in the area, highlighting a relatively small yet stable workforce. With a cost-of-living index of 89.6, the lower living expenses in Jefferson City can enhance the overall purchasing power of the nurse anesthetist pay in Jefferson City MO. Local healthcare providers, including hospital systems, ambulatory surgery centers, and CRNA-owned practices, play a significant role in determining salary levels. Differences in pay can be influenced by factors such as call coverage rotations, which vary from 1-in-8 to 1-in-5, as well as OR efficiency bonuses and weekend differentials. For those seeking higher compensation, aligning with CRNA-owned practices that offer partnership tracks or exploring opportunities with locum tenens agencies can prove beneficial strategies to maximize earnings in this market.
More salary data for Jefferson City, MO:
Frequently Asked Questions
How much do nurse anesthetists make in Jefferson City, MO in 2026?
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Can nurse anesthetists make $100K in Jefferson City?
What is the cost-of-living adjusted nurse anesthetist salary in Jefferson City?
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $201,949 for nurse anesthetistsin the Jefferson City metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Jefferson City is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov