Nurse Anesthetist Salary in Tupelo, MS: $211,231 (2026)
Quick Answer:A full-time nurse anesthetist in Tupelo, MS earns a median $211,231/year (≈ $101.55/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Tupelo's price level (14% below national, BEA RPP 85.7), that paycheck buys what $246,477 would nationally. Nominal pay sits 1.0% below the Mississippi state average.
Based on BLS state-level estimates · View source
In 2026, the projected median annual salary for nurse anesthetists in Tupelo, Mississippi, is $211,231. This figure illustrates a distinct variance compared to the national median of $248,893, placing it about 15.13% below that benchmark. Local nurse anesthetist pay ranges from $135,914 at the 10th percentile to $287,576 at the 90th percentile. These estimates derive from the Bureau of Labor Statistics (BLS) 2025 data, adjusted for regional price parities and the cost of living in Tupelo, which is indexed at 85.7, indicating a lower-than-average expense compared to the national norm. Such compensation positioning is influenced by the state's status under the Anesthesia Care Team model, where nurse anesthetists often collaborate with anesthesiologists, impacting not only salary potential but also job market dynamics.
About the Tupelo Market
Salary estimated from Mississippi average ($205,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $135,914 | $65.34 |
| Lower Range (P25) | $193,509 | $93.03 |
| Median (P50)(typical) | $211,231 | $101.55 |
| Upper Range (P75) | $255,822 | $122.99 |
| Top Earners (P90) | $287,576 | $138.25 |
Median Salary Position
15.13% below the national average
2026 Salary Percentile Distribution in Tupelo
In Tupelo, MS, the nurse anesthetist salary spread from the 10th to 90th percentile is $151,662 (2026 est.). At $211,231, the local median is 15.13% below the national median of $248,893.
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At 40 hours/week in Tupelo: You'd be above the median
How Tupelo Nurse Anesthetist Pay Compares
Tupelo median: $211,231/year (2026)
| Compared To | Median Salary | Tupelo Pays |
|---|---|---|
| Mississippi Average | $213,365 | -1.00% less |
| National Average | $248,893 | -15.13% less |
Nurse Anesthetists in Tupelo, MS earn a median of $211,231 per year (2026 est.), which is 15.13% lower than the national median of $248,893 and 1.00% below the Mississippi state average of $213,365.
Cost-of-Living Adjusted Salary
Tupelo has a cost of living 14.30% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Tupelo, MS has a cost-of-living index of 85.7 (below the national average of 100). A nurse anesthetist earning $211,231 nominally has purchasing power equivalent to $246,477 in an average-cost city — an effective 16.69% boost.
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2019 BLS Actual
$148,341
2025 BLS Actual
$200,790
2026 Current Est.
$211,231
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Tupelo (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $148,341 | Actual |
| 2020 | $155,801 | Actual |
| 2021 | $166,011 | Actual |
| 2022 | $172,359 | Actual |
| 2023 | $180,473 | Actual |
| 2024 | $173,980 | Actual |
| 2025 | $200,790 | Actual |
| 2026(current) | $211,231 | Estimated |
| 2027 | $222,215 | Projected |
Based on 7 years of BLS OEWS data for the Tupelo metropolitan area, the median nurse anesthetist salary grew 35.4% from $148,341 (2019) to $200,790 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $222,215 by 2027 — a total increase of $73,874 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Tupelo metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $135,914 – $193,509 |
| 3-5 years (Mid Career) | $193,509 – $211,231 |
| 5+ years (Experienced) | $211,231 – $255,822 |
| 10+ years (Top Earner) | $255,822 – $287,576 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Tupelo
With only seven nurse anesthetists currently employed in Tupelo, the job market remains relatively tight, suggesting opportunities for those entering the field. The cost of living index of 85.7 enhances the purchasing power of nurse anesthetists, as lower living expenses mean their salaries can stretch further in Tupelo. Top-paying employers include local hospital systems and CRNA-owned anesthesia group practices, which tend to offer more favorable compensation structures, including potential profit-sharing options. The spread in salaries among nurse anesthetists can arise from factors such as call coverage rotations and weekend differentials, with those taking on heavier workloads typically earning more. For maximizing compensation, aspiring nurse anesthetists in Tupelo should consider roles that provide not only competitive salaries but also opportunities for partnership tracks or performance bonuses, allowing them to take full advantage of the existing market trends.
More salary data for Tupelo, MS:
Frequently Asked Questions
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $200,790 for nurse anesthetistsin the Tupelo metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Tupelo is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov