Nurse Anesthetist Salary in Holyoke, MA: $263,802 (2026)
Quick Answer:A full-time nurse anesthetist in Holyoke, MA earns a median $263,802/year (≈ $126.83/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1151). Once you factor in Holyoke's price level (9% above national, BEA RPP 108.5), that paycheck buys what $243,135 would nationally. Nominal pay sits 2.3% below the Massachusetts state average.
Based on BLS state-level estimates · View source

In Holyoke, Massachusetts, the 2026 median annual salary for nurse anesthetists is projected to reach $263,802, reflecting a competitive positioning above the national median of $248,893. The salary range for this profession in the area varies significantly, with starting salaries around $171,655 and opportunities for more experienced practitioners approaching $377,652. These figures, derived from 2025 BLS data and adjusted for local cost factors, highlight the diverse earning potential in the region. Factors such as call coverage commitments and workload expectations greatly impact this variance, as professionals balance between fulfilling essential duties and enjoying a desirable lifestyle in Holyoke.
About the Holyoke Market
Salary estimated from Massachusetts average ($235,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $171,655 | $82.53 |
| Lower Range (P25) | $227,012 | $109.15 |
| Median (P50)(typical) | $263,802 | $126.83 |
| Upper Range (P75) | $330,765 | $159.02 |
| Top Earners (P90) | $377,652 | $181.56 |
Median Salary Position
5.99% above the national average
2026 Salary Percentile Distribution in Holyoke
In Holyoke, MA, the nurse anesthetist salary spread from the 10th to 90th percentile is $205,997 (2026 est.). At $263,802, the local median is 5.99% above the national median of $248,893.
Salary Calculator
At 40 hours/week in Holyoke: You'd be in the lower-middle range
How Holyoke Nurse Anesthetist Pay Compares
Holyoke median: $263,802/year (2026)
| Compared To | Median Salary | Holyoke Pays |
|---|---|---|
| Massachusetts Average | $270,012 | -2.30% less |
| National Average | $248,893 | +5.99% more |
Nurse Anesthetists in Holyoke, MA earn a median of $263,802 per year (2026 est.), which is 5.99% higher than the national median of $248,893 and 2.30% below the Massachusetts state average of $270,012.
Cost-of-Living Adjusted Salary
Holyoke has a cost of living 8.50% above the national average.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Holyoke, MA has a cost-of-living index of 108.5 (above the national average of 100). While the nominal salary of $263,802 is competitive, the higher cost of living reduces purchasing power to an effective $243,135 — a 7.83% reduction.
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2019 BLS Actual
$185,260
2025 BLS Actual
$250,762
2026 Current Est.
$263,802
2019–2027 Growth
+49.8%
Salary Trajectory for Nurse Anesthetists in Holyoke (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $185,260 | Actual |
| 2020 | $194,577 | Actual |
| 2021 | $207,327 | Actual |
| 2022 | $215,255 | Actual |
| 2023 | $225,388 | Actual |
| 2024 | $249,077 | Actual |
| 2025 | $250,762 | Actual |
| 2026(current) | $263,802 | Estimated |
| 2027 | $277,519 | Projected |
Based on 7 years of BLS OEWS data for the Holyoke metropolitan area, the median nurse anesthetist salary grew 35.4% from $185,260 (2019) to $250,762 (2025). At a 5.20% compound annual growth rate, salaries are projected to reach $277,519 by 2027 — a total increase of $92,259 (49.80%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Holyoke metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $171,655 – $227,012 |
| 3-5 years (Mid Career) | $227,012 – $263,802 |
| 5+ years (Experienced) | $263,802 – $330,765 |
| 10+ years (Top Earner) | $330,765 – $377,652 |
CRNA salary ranges estimated from BLS percentile data. Individual nurse anesthetist compensation varies by employer, certifications, and specialization.
Nurse Anesthetist Job Market in Holyoke
Currently, there are seven employed nurse anesthetists in Holyoke, with the local job market demonstrating moderate strength despite the relatively small number of practitioners. The cost of living index stands at 108.5, indicating higher-than-average living expenses, which could influence the take-home purchasing power for these specialists. Among various employers, hospital systems and ambulatory surgery centers often offer the most attractive compensation packages, while CRNA-owned anesthesia groups provide options for partnership that can yield increased financial benefits over time. Differences in pay are largely driven by factors such as the type of employment—W-2 vs. 1099 structures—and variations in call schedules, which can range from 1-in-8 to 1-in-5 rotations. To maximize earnings, nurse anesthetists should consider negotiating their contracts, focusing on roles that facilitate productivity bonuses and exploring opportunities in facilities that value experienced CRNAs while providing adequate support in the Anesthesia Care Team model.
More salary data for Holyoke, MA:
Frequently Asked Questions
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $250,762 for nurse anesthetistsin the Holyoke metropolitan area. A 5.20% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Holyoke is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov