Entry-Level Nurse Anesthetist Salary in Knoxville, TN: $147,722 (2026)
Quick Answer:New nurse anesthetists entering the Knoxville, TN job market in 2026 can expect a starting salary around $147,722 (BLS 10th-percentile benchmark for SOC 29-1151, projected from 2025 OEWS data). Stripping out Knoxville's local price level (BEA RPP 92.6 — 7% below national), a first-year paycheck buys what $159,580 would in average-cost America. Most reach the city median ($225,023) within a few years of clinical practice.
Official BLS data · View source

In 2026, Knoxville's entry-level nurse anesthetist salary is projected to start at $147,722, which may feel relatively modest compared to the city’s median salary of $225,023. This gap highlights an essential reality for new graduates entering the field; however, there is potential for swift salary growth, with early-career professionals likely progressing toward $196,335 within three to five years. The projected annual median for nurse anesthetists in Knoxville suggests that while starting salaries are below the national average, early-career salaries do align with anticipated local growth. For new graduates in TN, Knoxville presents a promising market with adequate opportunities for both immediate employment and professional development.
Career Earnings Timeline in Knoxville
New Graduate
Early Career
Mid Career
Experienced
Salary progression estimated from BLS percentile data. Actual progression varies by employer, certifications, and specialization.
2026 Salary Percentile Distribution in Knoxville
Entry-level nurse anesthetists in Knoxville, TN typically start between $147,722 and $196,335 per year (2026 est.). The full salary range spans $102,338 from the 10th to 90th percentile, with the local median at $225,023 — 9.59% below the national median.
Return on Investment
The average nursing program cost in Tennessee of $85,000 represents just 57.54% of the starting nurse anesthetist pay ($147,722/year) in Knoxville. Most graduates begin earning back their investment from day one, though actual ROI varies based on living expenses, loan interest, and the 2-year opportunity cost of schooling.
Program cost estimates based on COA-accredited (Council on Accreditation of Nurse Anesthesia Educational Programs) DNP/DNAP program data and AANA member tuition surveys. Tuition-only averages; actual costs vary significantly by institution type (public vs. private university) and residency status. Most programs require 1+ years ICU RN experience before admission.
CRNA Salary Negotiation Tips for New Graduates in Knoxville
- 1Research the Knoxville market: entry-level nurse anesthetist pay ranges from $147,722 to $196,335, so aim for at least the 25th percentile if you have strong credentials.
- 2Highlight any additional certifications or specialty training within the nursing field — employers in TN often pay a premium for expanded scope of work.
- 3Evaluate the full compensation package — in Knoxville, benefits like health insurance, continuing-education allowances, and schedule flexibility can add 20-30% to your effective compensation.
- 4Consider starting with a larger hospital system or multi-site employer in Knoxville for competitive entry-level pay and structured mentorship, then move to a smaller employer once you have 2-3 years of experience.
- 5Knoxville's below-average cost of living means your starting salary goes further here compared to many larger metro areas.
Nurse Anesthetist Compensation Range
The nurse anesthetist wage spread in Knoxville is $102,338 ( 69.28%) between entry-level and top earners. Starting at $147,722, experienced hygienists can earn up to $250,060.
Represents the current salary spread across experience levels, not projected career growth rate.
2019 BLS Actual
$111,280
2025 BLS Actual
$140,420
2026 Current Est.
$147,722
2019–2027 Growth
+39.7%
Salary Trajectory for Nurse Anesthetists in Knoxville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 5.20% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $111,280 | Actual |
| 2020 | $120,260 | Actual |
| 2021 | $119,246 | Actual |
| 2022 | $137,000 | Actual |
| 2023 | $171,020 | Actual |
| 2024 | $176,210 | Actual |
| 2025 | $140,420 | Actual |
| 2026(current) | $147,722 | Estimated |
| 2027 | $155,403 | Projected |
Entry-level nurse anesthetist compensation (10th percentile) in Knoxville, TN grew 26.2% over 7 years based on actual BLS metropolitan area surveys, rising from $111,280 in 2019 to $140,420 in 2025. By 2027, starting salaries are projected to reach $155,403. New graduates entering the Knoxville job market can expect continued year-over-year gains.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Knoxville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 5.20% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Starting Your nursing Career in Knoxville
Employers in Knoxville that typically hire new grad nurse anesthetists include major academic medical centers, which provide exposure to a wide variety of cases such as cardiac, pediatric, and transplant surgeries. For those seeking a more structured and supportive environment, large hospital systems often implement formal transition-to-practice programs specifically tailored for new graduates. To enhance starting pay and expand career opportunities, obtaining a CRNA license through the state board of nursing and NBCRNA certification is essential. Additionally, further credentials such as optional fellowships in specialized areas and pursuit of a DNP or DNAP terminal degree can greatly improve marketability. During the first one to three years, it’s important to set realistic salary expectations based on incremental growth, especially within the context of Tennessee's hybrid CRNA practice model. Here, CRNAs can operate independently without anesthesiologist supervision, which further supports the shift toward the growing CRNA-owned group-practice model, reflecting a positive trend for new professionals in the field.
More salary data for Knoxville, TN:
Frequently Asked Questions
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Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
Entry-level salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The 10th percentile (entry-level) is used as the starting salary benchmark for new nursing graduates. A 5.20% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to project current 2026 entry-level compensation in Knoxville. Program costs are averages and actual tuition varies by institution. ROI calculations are simplified estimates.
Data Sources & Methodology
Source: BLS, OEWS, 6-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 5.20%, derived from historical BLS wage trends for nurse anesthetists (SOC 29-1151).
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov