Nurse Anesthetists (CRNA) Salary

San Jose vs Santa Cruz: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between San Jose, CA and Santa Cruz, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Jose, CA
$304,151
$146.23/hr
Santa Cruz, CA
$281,525
$135.35/hr

Side-by-Side Comparison

MetricSan Jose, CASanta Cruz, CA
Median Salary$304,151$281,525
Hourly Rate$146.23$135.35
Entry Level (P10)$179,753$193,403
25th Percentile$267,010$250,385
75th Percentile$382,409$342,566
Top Earner (P90)$446,799$417,245
Total Employed16812
Side-by-side bar chart comparing San Jose ($304,151) and Santa Cruz ($281,525) nurse anesthetist salaries.San JoseSanta CruzMedian Salary$304,151$281,525Entry Level (P10)$179,753$193,403Top Earner (P90)$446,799$417,245US Median $248,893

Verdict

San Jose, CA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Santa Cruz.

The salary gap between San Jose and Santa Cruz is $22,626 (8.04%). San Jose's median is +22.20% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Jose spans $267,046,Santa Cruz spans $223,842. San Jose has a wider pay range, meaning more potential for high earners but also more variation.

San Jose
P10 (Entry)$179,753
P25$267,010
Median$304,151
P75$382,409
P90 (Top)$446,799
Santa Cruz
P10 (Entry)$193,403
P25$250,385
Median$281,525
P75$342,566
P90 (Top)$417,245

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Jose ($268,922 effective) pays 8.04% more than Santa Cruz ($248,917 effective).

San Jose
Nominal: $304,151
CoL Index: 113.1
Adjusted: $268,922
Santa Cruz
Nominal: $281,525
CoL Index: 113.1
Adjusted: $248,917

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Jose if…

  • Higher median salary ($304,151/year)
  • Better top-earner potential ($446,799)
  • Larger job market (168 employed)
  • Better purchasing power (CoL-adjusted: $268,922)
  • You prefer the California area and lifestyle

Choose Santa Cruz if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in San Jose grew 27.3% from 2022 to 2025, compared to -9.0% growth in Santa Cruz over the same period.

San Jose, CA

+27.3%

$227,100 (2022) → $289,117 (2025)

Santa Cruz, CA

+-9.0%

$294,089 (2024) → $267,609 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: San Jose or Santa Cruz?

San Jose has a higher median nurse anesthetist salary at $304,151/year, compared to Santa Cruz at $281,525/year — a difference of $22,626 (8.04%).

What is the hourly rate difference between San Jose and Santa Cruz?

San Jose nurse anesthetists earn $146.23/hr while Santa Cruz hygienists earn $135.35/hr (2026 est.).

Should I relocate from San Jose to Santa Cruz as a nurse anesthetist?

Consider more than just salary when comparing San Jose and Santa Cruz. Factor in cost of living (CoL-adjusted: San Jose = $268,922, Santa Cruz = $248,917), job availability (168 vs 12 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in San Jose vs Santa Cruz?

Entry-level (10th percentile) nurse anesthetists earn $179,753 in San Jose and $193,403 in Santa Cruz. The Santa Cruz area offers higher starting salaries.

Related Comparisons

AJ

Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov