Nurse Anesthetists (CRNA) Salary

San Francisco vs Santee: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between San Francisco, CA and Santee, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$306,024
$147.12/hr
Santee, CA
$283,465
$136.28/hr

Side-by-Side Comparison

MetricSan Francisco, CASantee, CA
Median Salary$306,024$283,465
Hourly Rate$147.12$136.28
Entry Level (P10)$183,733$183,488
25th Percentile$252,943$243,675
75th Percentile$391,710$353,498
Top Earner (P90)$473,097$395,720
Total Employed1429
Side-by-side bar chart comparing San Francisco ($306,024) and Santee ($283,465) nurse anesthetist salaries.San FranciscoSanteeMedian Salary$306,024$283,465Entry Level (P10)$183,733$183,488Top Earner (P90)$473,097$395,720US Median $248,893

Verdict

San Francisco, CA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Santee.

The salary gap between San Francisco and Santee is $22,559 (7.96%). San Francisco's median is +22.95% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $289,364,Santee spans $212,232. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$183,733
P25$252,943
Median$306,024
P75$391,710
P90 (Top)$473,097
Santee
P10 (Entry)$183,488
P25$243,675
Median$283,465
P75$353,498
P90 (Top)$395,720

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($270,578 effective) pays 7.96% more than Santee ($250,632 effective).

San Francisco
Nominal: $306,024
CoL Index: 113.1
Adjusted: $270,578
Santee
Nominal: $283,465
CoL Index: 113.1
Adjusted: $250,632

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($306,024/year)
  • Better top-earner potential ($473,097)
  • Larger job market (142 employed)
  • Better purchasing power (CoL-adjusted: $270,578)
  • You prefer the California area and lifestyle

Choose Santee if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in San Francisco grew 23.7% from 2022 to 2025, compared to -9.0% growth in Santee over the same period.

San Francisco, CA

+23.7%

$235,120 (2022) → $290,897 (2025)

Santee, CA

+-9.0%

$296,115 (2024) → $269,453 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: San Francisco or Santee?

San Francisco has a higher median nurse anesthetist salary at $306,024/year, compared to Santee at $283,465/year — a difference of $22,559 (7.96%).

What is the hourly rate difference between San Francisco and Santee?

San Francisco nurse anesthetists earn $147.12/hr while Santee hygienists earn $136.28/hr (2026 est.).

Should I relocate from San Francisco to Santee as a nurse anesthetist?

Consider more than just salary when comparing San Francisco and Santee. Factor in cost of living (CoL-adjusted: San Francisco = $270,578, Santee = $250,632), job availability (142 vs 9 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in San Francisco vs Santee?

Entry-level (10th percentile) nurse anesthetists earn $183,733 in San Francisco and $183,488 in Santee. The San Francisco area offers higher starting salaries.

Related Comparisons

AJ

Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov