Nurse Anesthetists (CRNA) Salary

San Francisco vs San Marcos: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between San Francisco, CA and San Marcos, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Francisco, CA
$306,024
$147.12/hr
San Marcos, CA
$281,458
$135.32/hr

Side-by-Side Comparison

MetricSan Francisco, CASan Marcos, CA
Median Salary$306,024$281,458
Hourly Rate$147.12$135.32
Entry Level (P10)$183,733$177,793
25th Percentile$252,943$239,518
75th Percentile$391,710$348,564
Top Earner (P90)$473,097$417,012
Total Employed14217
Side-by-side bar chart comparing San Francisco ($306,024) and San Marcos ($281,458) nurse anesthetist salaries.San FranciscoSan MarcosMedian Salary$306,024$281,458Entry Level (P10)$183,733$177,793Top Earner (P90)$473,097$417,012US Median $248,893

Verdict

San Francisco, CA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to San Marcos.

The salary gap between San Francisco and San Marcos is $24,566 (8.73%). San Francisco's median is +22.95% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Francisco spans $289,364,San Marcos spans $239,219. San Francisco has a wider pay range, meaning more potential for high earners but also more variation.

San Francisco
P10 (Entry)$183,733
P25$252,943
Median$306,024
P75$391,710
P90 (Top)$473,097
San Marcos
P10 (Entry)$177,793
P25$239,518
Median$281,458
P75$348,564
P90 (Top)$417,012

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($270,578 effective) pays 8.73% more than San Marcos ($248,858 effective).

San Francisco
Nominal: $306,024
CoL Index: 113.1
Adjusted: $270,578
San Marcos
Nominal: $281,458
CoL Index: 113.1
Adjusted: $248,858

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Francisco if…

  • Higher median salary ($306,024/year)
  • Better top-earner potential ($473,097)
  • Larger job market (142 employed)
  • Better purchasing power (CoL-adjusted: $270,578)
  • You prefer the California area and lifestyle

Choose San Marcos if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in San Francisco grew 23.7% from 2022 to 2025, compared to -9.0% growth in San Marcos over the same period.

San Francisco, CA

+23.7%

$235,120 (2022) → $290,897 (2025)

San Marcos, CA

+-9.0%

$294,019 (2024) → $267,546 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: San Francisco or San Marcos?

San Francisco has a higher median nurse anesthetist salary at $306,024/year, compared to San Marcos at $281,458/year — a difference of $24,566 (8.73%).

What is the hourly rate difference between San Francisco and San Marcos?

San Francisco nurse anesthetists earn $147.12/hr while San Marcos hygienists earn $135.32/hr (2026 est.).

Should I relocate from San Francisco to San Marcos as a nurse anesthetist?

Consider more than just salary when comparing San Francisco and San Marcos. Factor in cost of living (CoL-adjusted: San Francisco = $270,578, San Marcos = $248,858), job availability (142 vs 17 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in San Francisco vs San Marcos?

Entry-level (10th percentile) nurse anesthetists earn $183,733 in San Francisco and $177,793 in San Marcos. The San Francisco area offers higher starting salaries.

Related Comparisons

AJ

Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov