Nurse Anesthetists (CRNA) Salary

San Diego vs Santa Clarita: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between San Diego, CA and Santa Clarita, CA. All figures are 2026 estimates projected from BLS 2025 data.

San Diego, CA
$298,265
$143.40/hr
Santa Clarita, CA
$287,612
$138.27/hr

Side-by-Side Comparison

MetricSan Diego, CASanta Clarita, CA
Median Salary$298,265$287,612
Hourly Rate$143.40$138.27
Entry Level (P10)$190,201$187,053
25th Percentile$255,081$249,634
75th Percentile$381,779$368,143
Top Earner (P90)$445,118$436,563
Total Employed30741
Side-by-side bar chart comparing San Diego ($298,265) and Santa Clarita ($287,612) nurse anesthetist salaries.San DiegoSanta ClaritaMedian Salary$298,265$287,612Entry Level (P10)$190,201$187,053Top Earner (P90)$445,118$436,563US Median $248,893

Verdict

San Diego, CA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Santa Clarita.

The salary gap between San Diego and Santa Clarita is $10,653 (3.70%). San Diego's median is +19.84% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in San Diego spans $254,917,Santa Clarita spans $249,510. San Diego has a wider pay range, meaning more potential for high earners but also more variation.

San Diego
P10 (Entry)$190,201
P25$255,081
Median$298,265
P75$381,779
P90 (Top)$445,118
Santa Clarita
P10 (Entry)$187,053
P25$249,634
Median$287,612
P75$368,143
P90 (Top)$436,563

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Diego ($263,718 effective) pays 3.70% more than Santa Clarita ($254,299 effective).

San Diego
Nominal: $298,265
CoL Index: 113.1
Adjusted: $263,718
Santa Clarita
Nominal: $287,612
CoL Index: 113.1
Adjusted: $254,299

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose San Diego if…

  • Higher median salary ($298,265/year)
  • Better top-earner potential ($445,118)
  • Larger job market (307 employed)
  • Better purchasing power (CoL-adjusted: $263,718)
  • You prefer the California area and lifestyle

Choose Santa Clarita if…

  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in San Diego grew -9.0% from 2024 to 2025, compared to -9.0% growth in Santa Clarita over the same period.

San Diego, CA

+-9.0%

$311,576 (2024) → $283,522 (2025)

Santa Clarita, CA

+-9.0%

$300,447 (2024) → $273,395 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: San Diego or Santa Clarita?

San Diego has a higher median nurse anesthetist salary at $298,265/year, compared to Santa Clarita at $287,612/year — a difference of $10,653 (3.70%).

What is the hourly rate difference between San Diego and Santa Clarita?

San Diego nurse anesthetists earn $143.40/hr while Santa Clarita hygienists earn $138.27/hr (2026 est.).

Should I relocate from San Diego to Santa Clarita as a nurse anesthetist?

Consider more than just salary when comparing San Diego and Santa Clarita. Factor in cost of living (CoL-adjusted: San Diego = $263,718, Santa Clarita = $254,299), job availability (307 vs 41 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in San Diego vs Santa Clarita?

Entry-level (10th percentile) nurse anesthetists earn $190,201 in San Diego and $187,053 in Santa Clarita. The San Diego area offers higher starting salaries.

Related Comparisons

AJ

Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov