San Diego vs San Mateo: Nurse Anesthetist Salary (2026)
Compare nurse anesthetist salaries between San Diego, CA and San Mateo, CA. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | San Diego, CA | San Mateo, CA |
|---|---|---|
| Median Salary | $298,265▲ | $284,483 |
| Hourly Rate | $143.40▲ | $136.77 |
| Entry Level (P10) | $190,201▲ | $172,860 |
| 25th Percentile | $255,081▲ | $253,444 |
| 75th Percentile | $381,779▲ | $352,809 |
| Top Earner (P90) | $445,118▲ | $423,748 |
| Total Employed | 307▲ | 21 |
Verdict
San Diego, CA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to San Mateo.
The salary gap between San Diego and San Mateo is $13,782 (4.84%). San Diego's median is +19.84% compared to the US national median of $248,893.
Salary Range Comparison
The full salary range (10th to 90th percentile) in San Diego spans $254,917,San Mateo spans $250,888. San Diego has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, San Diego ($263,718 effective) pays 4.84% more than San Mateo ($251,532 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose San Diego if…
- ✓Higher median salary ($298,265/year)
- ✓Better top-earner potential ($445,118)
- ✓Larger job market (307 employed)
- ✓Better purchasing power (CoL-adjusted: $263,718)
- ✓You prefer the California area and lifestyle
Choose San Mateo if…
- ✓You prefer the California area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in San Diego grew -9.0% from 2024 to 2025, compared to -9.0% growth in San Mateo over the same period.
San Diego, CA
$311,576 (2024) → $283,522 (2025)
San Mateo, CA
$297,179 (2024) → $270,421 (2025)
View Full Salary Data
San Diego, CA
San Mateo, CA
Frequently Asked Questions
Which city pays nurse anesthetists more: San Diego or San Mateo?
What is the hourly rate difference between San Diego and San Mateo?
Should I relocate from San Diego to San Mateo as a nurse anesthetist?
What do entry-level nurse anesthetists earn in San Diego vs San Mateo?
Related Comparisons
Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov