Nurse Anesthetists (CRNA) Salary

Des Moines vs Sioux City: Nurse Anesthetist Salary (2026)

Compare nurse anesthetist salaries between Des Moines, IA and Sioux City, IA. All figures are 2026 estimates projected from BLS 2025 data.

Des Moines, IA
$250,029
$120.20/hr
Sioux City, IA
$226,624
$108.96/hr

Side-by-Side Comparison

MetricDes Moines, IASioux City, IA
Median Salary$250,029$226,624
Hourly Rate$120.20$108.96
Entry Level (P10)$237,500$146,781
25th Percentile$237,500$194,878
75th Percentile$295,728$277,720
Top Earner (P90)$337,724$316,478
Total Employed8013
Side-by-side bar chart comparing Des Moines ($250,029) and Sioux City ($226,624) nurse anesthetist salaries.Des MoinesSioux CityMedian Salary$250,029$226,624Entry Level (P10)$237,500$146,781Top Earner (P90)$337,724$316,478US Median $248,893

Verdict

Des Moines, IA offers better overall compensation for nurse anesthetists, winning 4 out of 4 metrics compared to Sioux City.

The salary gap between Des Moines and Sioux City is $23,405 (10.33%). Des Moines's median is +0.46% compared to the US national median of $248,893.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Des Moines spans $100,224,Sioux City spans $169,697. Sioux City has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse anesthetists.

Des Moines
P10 (Entry)$237,500
P25$237,500
Median$250,029
P75$295,728
P90 (Top)$337,724
Sioux City
P10 (Entry)$146,781
P25$194,878
Median$226,624
P75$277,720
P90 (Top)$316,478

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, Des Moines ($272,657 effective) pays 8.76% more than Sioux City ($250,690 effective).

Des Moines
Nominal: $250,029
CoL Index: 91.701
Adjusted: $272,657
Sioux City
Nominal: $226,624
CoL Index: 90.4
Adjusted: $250,690

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Des Moines if…

  • Higher median salary ($250,029/year)
  • Better top-earner potential ($337,724)
  • Larger job market (80 employed)
  • Better purchasing power (CoL-adjusted: $272,657)
  • You prefer the Iowa area and lifestyle

Choose Sioux City if…

  • You prefer the Iowa area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Des Moines grew 25.0% from 2019 to 2025, compared to 24.4% growth in Sioux City over the same period.

Des Moines, IA

+25.0%

$190,210 (2019) → $237,670 (2025)

Sioux City, IA

+24.4%

$173,180 (2021) → $215,422 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse anesthetists more: Des Moines or Sioux City?

Des Moines has a higher median nurse anesthetist salary at $250,029/year, compared to Sioux City at $226,624/year — a difference of $23,405 (10.33%).

What is the hourly rate difference between Des Moines and Sioux City?

Des Moines nurse anesthetists earn $120.20/hr while Sioux City hygienists earn $108.96/hr (2026 est.).

Should I relocate from Des Moines to Sioux City as a nurse anesthetist?

Consider more than just salary when comparing Des Moines and Sioux City. Factor in cost of living (CoL-adjusted: Des Moines = $272,657, Sioux City = $250,690), job availability (80 vs 13 employed), commute, and career growth potential.

What do entry-level nurse anesthetists earn in Des Moines vs Sioux City?

Entry-level (10th percentile) nurse anesthetists earn $237,500 in Des Moines and $146,781 in Sioux City. The Des Moines area offers higher starting salaries.
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Written by Alexandra Johnson, MSN, CRNA

Career Analyst

Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.

Clinically reviewed by Michael Lee, DNP, CRNAData verified by Fatima Ahmad, MSN, CRNA

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov