Charleston vs Columbia: Nurse Anesthetist Salary (2026)
Compare nurse anesthetist salaries between Charleston, SC and Columbia, SC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Charleston, SC | Columbia, SC |
|---|---|---|
| Median Salary | $240,634 | $285,460▲ |
| Hourly Rate | $115.69 | $137.24▲ |
| Entry Level (P10) | $175,800 | $225,128▲ |
| 25th Percentile | $235,585 | $235,985▲ |
| 75th Percentile | $303,386▲ | $302,639 |
| Top Earner (P90) | $434,918▲ | $350,348 |
| Total Employed | N/A | 210 |
Verdict
Columbia, SC offers better overall compensation for nurse anesthetists, winning 3 out of 4 metrics compared to Charleston.
The salary gap between Charleston and Columbia is $44,826 (18.63%). Columbia's median is +14.69% compared to the US national median of $248,893.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Charleston spans $259,118,Columbia spans $125,220. Charleston has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Columbia ($304,777 effective) pays 27.87% more than Charleston ($238,341 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Charleston if…
- ✓Better top-earner potential ($434,918)
- ✓You prefer the South Carolina area and lifestyle
Choose Columbia if…
- ✓Higher median salary ($285,460/year)
- ✓Larger job market (210 employed)
- ✓Better purchasing power (CoL-adjusted: $304,777)
- ✓You prefer the South Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, nurse anesthetist salaries in Charleston grew 43.5% from 2019 to 2025, compared to 51.1% growth in Columbia over the same period.
Charleston, SC
$159,380 (2019) → $228,740 (2025)
Columbia, SC
$179,550 (2019) → $271,350 (2025)
View Full Salary Data
Charleston, SC
Columbia, SC
Frequently Asked Questions
Which city pays nurse anesthetists more: Charleston or Columbia?
What is the hourly rate difference between Charleston and Columbia?
Should I relocate from Charleston to Columbia as a nurse anesthetist?
What do entry-level nurse anesthetists earn in Charleston vs Columbia?
Written by Alexandra Johnson, MSN, CRNA
Career Analyst
Alexandra Johnson has 10 years of experience as a nurse anesthetist. She specializes in anesthesia for orthopedic surgeries. She works in a regional medical center.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 5.20% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Alexandra Johnson, MSN, CRNA, a licensed nurse anesthetist with 10+ years of clinical experience. · View source data at BLS.gov